Protein modifications by advanced glycation end products (AGEs) in human clear cell renal cell carcinoma

Protein modifications by advanced glycation end products (AGEs) in human clear cell renal cell carcinoma

Abstract Background The development of cancer is often associated with altered glycolytic processes, resulting in the accumulation of highly reactive dicarbonyl compounds that promote protein modifications through advanced glycation end products (AGEs). This study aimed to quantify and identify the...

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Main Authors: Agnieszka Gęgotek, Justyna Brańska-Januszewska, Paweł Samocik, Robert Kozłowski, Mariusz Koda, Neven Zarkovic, Elżbieta Skrzydlewska, Halina Ostrowska
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
Advanced glycation end products (AGEs)
Protein modification
Proteomics
Kidney disease
Tumor
Clear cell renal cell carcinoma (ccRCC)
Online Access:https://doi.org/10.1186/s12967-025-06958-6
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https://doi.org/10.1186/s12967-025-06958-6

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