A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics

A translational protocol optimizes the isolation of plasma-derived extracellular vesicle proteomics

Abstract In translational research and clinical routine, liquid biopsy is a promising tool to direct individually targeted treatments. Among the components of liquid biopsy, extracellular vesicles (EVs) carry manyfold molecular cargo and are increasingly being studied for biomarker identification. I...

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Main Authors: Jussara Ríos de los Ríos Reséndiz, Freya Herrmann-Sim, Liliana Wilkesmann, Dominic Helm, Martin Schneider, Giorgia Campione, Klara Plügge, Giovanni Greiner, Leonie Lazaro García, Julia Berker, Karsten Richter, Lin Zielske, Wolf-Karsten Hofmann, Katharina Clemm von Hohenberg
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Extracellular vesicles
Liquid biopsy
Plasma
Translation
Proteomics
Pre-analytics
Online Access:https://doi.org/10.1038/s41598-025-08366-8
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https://doi.org/10.1038/s41598-025-08366-8

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