Gut microbiota metabolites, secretory immunoglobulin A and Bayley-III cognitive scores in children from the CHILD Cohort Study

Gut microbiota metabolites, secretory immunoglobulin A and Bayley-III cognitive scores in children from the CHILD Cohort Study

Background: Dysbiosis of the gut microbiota has been demonstrated in neurodevelopmental disorders but the underlying mechanisms that may explain these associations are poorly understood. Gut secretory immunoglobulin A (SIgA) binds pathogenic microbes, preventing mucosal penetration. Gut microbes als...

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Main Authors: Aline Davias, Myah Verghese, Sarah L. Bridgman, Hein M. Tun, Catherine J. Field, Matthew Hicks, Jacqueline Pei, Anne Hicks, Theo J. Moraes, Elinor Simons, Stuart E. Turvey, Padmaja Subbarao, James A. Scott, Piushkumar J. Mandhane, Anita L. Kozyrskyj
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Bayley-III scale of infant development
Infant gut microbiota
Secretory immunoglobulin A
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354625000043
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