Energy landscape of a Kv channel revealed by temperature steps while perturbing its electromechanical coupling
Abstract Voltage-dependent potassium channels (Kv) play a crucial role in membrane repolarization during action potentials. They undergo voltage-dependent structural conformational transitions according to their distribution across their energy landscape. Understanding these transitions helps us com...
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| Main Authors: | Bernardo I. Pinto-Anwandter, Carlos A. Z. Bassetto, Ramon Latorre, Francisco Bezanilla |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-58443-9 |
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