Lipid nephrotoxicity mediated by HIF-1α activation accelerates tubular injury in diabetic nephropathy
This study is intended to explore the effect of hypoxia-inducible factor-1α (HIF-1α) activation on lipid accumulation in the diabetic kidney. A type 1 diabetic rat model was established by STZ intraperitoneal injection. Cobalt chloride (CoCl2) and YC-1 were used as the HIF-1α activator and antagonis...
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Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2024-12-01
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Series: | Renal Failure |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2024.2347446 |
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