Sex differences in genotype frequency and the risk of polycythemia associated with rs13419896 and rs2790859 among Tibetan highlanders living in Tsarang, Mustang, Nepal

Sex differences in genotype frequency and the risk of polycythemia associated with rs13419896 and rs2790859 among Tibetan highlanders living in Tsarang, Mustang, Nepal

Abstract Background Tibetan highlanders have adapted to hypoxic environments through genetic mechanisms that avoid hemoglobin concentration increases and prevent polycythemia. Recently, sex differences in hemoglobin dynamics with age have been reported among Tibetan highlanders living in Tsarang. Ad...

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Bibliographic Details
Main Authors: Hiroaki Arima, Takayuki Nishimura, Sweta Koirala, Masayuki Nakano, Hiromu Ito, Tomo Ichikawa, Kishor Pandey, Basu Dev Pandey, Taro Yamamoto
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Physiological Anthropology
Subjects:
Sex difference
Tibetan highlander
Polycythemia
EGLN1
Mustang
Online Access:https://doi.org/10.1186/s40101-024-00372-5
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https://doi.org/10.1186/s40101-024-00372-5

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