Evaluation of PAMAM Dendrimer-Stabilized Gold Nanoparticles: Two-Stage Procedure Synthesis and Toxicity Assessment in MCF-7 Breast Cancer Cells

Evaluation of PAMAM Dendrimer-Stabilized Gold Nanoparticles: Two-Stage Procedure Synthesis and Toxicity Assessment in MCF-7 Breast Cancer Cells

Gold nanoparticles stabilized with polyamidoamine dendrimers are one of the potential candidates for use as a contrast agent in computed tomography and a drug delivery agent. This work demonstrates a rapid, two-step synthesis of such complexes, which are size-stable for up to 18 months. The first st...

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Bibliographic Details
Main Authors: Agnieszka Maria Kołodziejczyk, Magdalena Grala, Łukasz Kołodziejczyk
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
gold nanoparticles synthesis
AuNPs
PAMAM G4 dendrimers
atomic force microscopy
XTT tetrazolium salt reduction tests
cellular viability
Online Access:https://www.mdpi.com/1420-3049/30/9/2024
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https://www.mdpi.com/1420-3049/30/9/2024

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