Characterisation of the Self‐Sufficient Cytochrome P450 CYP116B234 From Rhodococcus globerulus and Its Suggested Native Role in 2‐Hydroxyphenylacetic Acid Metabolism

Characterisation of the Self‐Sufficient Cytochrome P450 CYP116B234 From Rhodococcus globerulus and Its Suggested Native Role in 2‐Hydroxyphenylacetic Acid Metabolism

ABSTRACT Cytochromes P450 (P450s) are exceptional biocatalysts that enable the selective oxidation of unactivated C–H bonds using molecular oxygen. Typically, auxiliary redox partner proteins deliver electrons from NAD(P)H to the P450, enabling oxygen activation. However, associating native redox pa...

Full description

Saved in:
Bibliographic Details
Main Authors: Simran Kundral, Hannah Beamish, Peter D. Giang, Lauren J. Salisbury, Amanda S. Nouwens, Sunil K. Khare, Paul V. Bernhardt, Jeffrey R. Harmer, Stephen G. Bell, James J. De Voss
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Microbial Biotechnology
Subjects:
biocatalysis
biodegradation
CYP116
cytochrome P450
oxidation
Online Access:https://doi.org/10.1111/1751-7915.70125
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1111/1751-7915.70125

Similar Items