Malaria-derived hemozoin skews dendritic cell responses to bacterial infections by reducing interferon gene-transcription by SWI/SNF-NuRD
Summary: Hemozoin (HZ), the malaria pigment, is associated with the disease when released during the pro-inflammatory blood stage and co-infections with bacteria lead to a more severe disease progression. The underlying mechanisms are poorly understood and, here, we show that the impact of co-exposu...
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| Main Authors: | Gintare Lasaviciute, Kanwal Tariq, Anaswara Sugathan, Jaclyn Quin, Mareike Polenkowski, Ioana Bujila, Oleksii Skorokhod, Marita Troye-Blomberg, Eva Sverremark-Ekström, Ann-Kristin Östlund Farrants |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225013070 |
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