A new mechanism of cancer initiation that involves the transformation of hepatocytes into preneoplastic single hepatocytes and minifoci positive for glutathione S‐transferase P‐form (GST‐P) in rat livers: 3D analysis using a vibratome

Abstract Background Cancer initiation has long been “unknowable” in biology and medicine. In 1987, however, Moore and our research group observed single hepatocytes and minifoci that were strongly positive for glutathione S‐transferase P‐form (GST‐P) in the rat liver as early as 2 to 3 days after in...

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Bibliographic Details
Main Author: Kimihiko Satoh
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.70165
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