Carbon Monoxide Stimulates Chondrocyte Mitochondria and Protects Mitochondria During Cartilage Injury

Carbon Monoxide Stimulates Chondrocyte Mitochondria and Protects Mitochondria During Cartilage Injury

<b><i>Objective:</i></b> Joint injury precipitates post-traumatic osteoarthritis (PTOA) via chondrocyte mitochondrial oxidative damage. Carbon monoxide (CO) is a small molecule with potent antioxidant and mitochondrial benefits in other tissues that have not been explored in...

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Bibliographic Details
Main Authors: Suryamin Liman, Madeline R. Hines, Piedad C. Gómez-Contreras, Emily Witt, Jacob S. Fisher, Kevin J. Lu, Lauren D. McNally, Alicia T. Cotoia, Maxwell Y. Sakyi, Brett A. Wagner, Michael S. Tift, Douglas Fredericks, Jessica E. Goetz, James D. Byrne, Mitchell C. Coleman
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
cartilage
carbon monoxide
mitochondria
glutathione
monochlorobimane
Online Access:https://www.mdpi.com/2076-3921/14/5/514
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