Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior.

Embryonic exposure to the endocrine disruptor vinclozolin during gonadal sex determination promotes an epigenetic reprogramming of the male germ-line that is associated with transgenerational adult onset disease states. Further analysis of this transgenerational phenotype on the brain demonstrated r...

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Bibliographic Details
Main Authors: Michael K Skinner, Matthew D Anway, Marina I Savenkova, Andrea C Gore, David Crews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003745&type=printable
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