Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling

Abstract Coagulation factors are responsible for blood clot formation yet have also non-canonical functions as signalling molecules. In this context, they can activate protease-activated receptors (PARs) ubiquitously expressed in the vasculature. During vascular repair, vascular smooth muscle cells...

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Bibliographic Details
Main Authors: Anxhela Habibi, Wolfram Ruf, Leon Schurgers
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-025-02066-6
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