Lack of Association between C1236T, G2677T/A and C3435T Variants of the ABCB1 Gene and Imatinib Response in Iranian Chronic Myeloid Leukemia Patients

Imatinib introduction caused to improve the clinical outcomes of chronic myeloid leukemia (CML) patients. Despite the significant effects of Imatinib, pharmacogenetic variables induced treatment resistant is also observed. Imatinib is known as a P-glycoprotein (P-gp) efflux pump substrate encoded by...

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Bibliographic Details
Main Authors: Maedeh Khosravi, Zahra Khalaj, Negar Nouri, Malihe Najaflu, Valiollah Mehrzad, Mohammad Forat-Yazdi, Fariborz Mokarian, Mansour Salehi
Format: Article
Language:English
Published: University of Tehran 2021-05-01
Series:Journal of Sciences, Islamic Republic of Iran
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Online Access:https://jsciences.ut.ac.ir/article_79822_369bda83edd5fcbb8eff934e739f6dee.pdf
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