New QSAR Models to Predict Human Transthyretin Disruption by Per- and Polyfluoroalkyl Substances (PFAS): Development and Application
Per- and polyfluoroalkyl substances (PFAS) are of concern because of their potential thyroid hormone system disruption by binding to human transthyretin (hTTR). However, the amount of experimental data is scarce. In this work, new classification and regression QSARs were developed to predict the hTT...
Saved in:
| Main Authors: | Marco Evangelista, Nicola Chirico, Ester Papa |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-07-01
|
| Series: | Toxics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6304/13/7/590 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Exposure to Per- and Polyfluoroalkyl Substances (PFASs) in Healthcare: Environmental and Clinical Insights
by: George Briassoulis, et al.
Published: (2025-07-01) -
Per and polyfluoroalkyl substances affect thyroid hormones for people with a history of exposure from drinking water
by: Taylor S. Noyes, et al.
Published: (2025-04-01) -
Serum levels of per- and polyfluoroalkylated substances and methylation of DNA from peripheral blood
by: Hanane Omichessan, et al.
Published: (2025-07-01) -
Paternal and maternal exposures to per- and polyfluoroalkyl substances (PFAS) and birth outcomes: a multi-country cohort study
by: Pengfei Guo, et al.
Published: (2025-07-01) -
Per- and polyfluoroalkyl substances (PFAS) in the cryosphere – occurrence, organismic accumulation, ecotoxicological impacts, transformation, and management strategies
by: Ashani Arulananthan, et al.
Published: (2025-04-01)