New QSAR Models to Predict Human Transthyretin Disruption by Per- and Polyfluoroalkyl Substances (PFAS): Development and Application

Per- and polyfluoroalkyl substances (PFAS) are of concern because of their potential thyroid hormone system disruption by binding to human transthyretin (hTTR). However, the amount of experimental data is scarce. In this work, new classification and regression QSARs were developed to predict the hTT...

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Bibliographic Details
Main Authors: Marco Evangelista, Nicola Chirico, Ester Papa
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/13/7/590
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