The Gut–Heart Axis and Its Role in Doxorubicin-Induced Cardiotoxicity: A Narrative Review

The Gut–Heart Axis and Its Role in Doxorubicin-Induced Cardiotoxicity: A Narrative Review

Doxorubicin is a widely used chemotherapy for the treatment of several types of cancer. However, its application is restricted due to adverse effects, particularly cardiotoxicity, which can progress to heart failure—a chronic and debilitating condition. Several mechanisms have been identified in the...

Full description

Saved in:
Bibliographic Details
Main Authors: Carolina Rodrigues Tonon, Amanda Gomes Pereira, Natália Fernanda Ferreira, Marina Gaiato Monte, Nayane Maria Vieira, Anderson Seiji Soares Fujimori, Paola da Silva Ballin, Sergio Alberto Rupp de Paiva, Leonardo Antonio Mamede Zornoff, Marcos Ferreira Minicucci, Bertha Furlan Polegato
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
Subjects:
gut microbiota
cardiac remodeling
cardiovascular disease
short-chain fatty acids
tight junctions
LPS
Online Access:https://www.mdpi.com/2076-2607/13/4/855
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2076-2607/13/4/855

Similar Items