Overcoming cancer treatment resistance: Unraveling the role of cancer-associated fibroblasts

The resistance to cancer treatment is a major clinical obstacle, being strongly influenced by the tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) are critical elements of the TME. CAFs are heterogeneous and are activated through diverse pathways. These CAFs engage in reciprocal in...

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Bibliographic Details
Main Authors: Xiaoyuan Wang, Yinuo Zhou, Yingzhuo Wang, Jiaxin Yang, Zhengqian Li, Fuliang Liu, Anni Wang, Zhenhao Gao, Chen Wu, Hang Yin
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of the National Cancer Center
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667005425000390
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