Influence of storage conditions on the toxicity of whole-cell pertussis vaccine in outbred mice

INTRODUCTION. Although whole-cell pertussis vaccine (WCPV) is highly effective, its widespread use is limited by adverse reactions (increased body temperature, administration site oedema, allergic reactions, and febrile seizures). Therefore, there is a need to explore strategies for reducing the tox...

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Main Authors: I. A. Alekseeva, D. N. Lepikhova, O. Yu. Borisova, A. S. Pimenova, I. Yu. Andrievskaya, I. V. Ibragimkhalilova
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2025-04-01
Series:Биопрепараты: Профилактика, диагностика, лечение
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Online Access:https://www.biopreparations.ru/jour/article/view/629
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