Linear ubiquitination of p31comet by HOIP couples cytokine response with mitotic regulation

Linear ubiquitination of p31comet by HOIP couples cytokine response with mitotic regulation

Abstract Background Inflammation and genomic instability are among the hallmarks of human cancer. Proinflammatory cytokines induce DNA damage through the accumulation of reactive oxygen and nitrogen species (RONS), which often leads to base alternations. The link between proinflammatory cytokines an...

Full description

Saved in:
Bibliographic Details
Main Authors: Yifeng Gao, Qing Yin, Yaser Gamallat, Michael G. Grant, Aidan H. Snell, Xingxing Shi, Lara N. Ulstad, Arshita Singh, Tingan Chen, Joseph O. Johnson, Dorina Avram, Lixin Wan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell & Bioscience
Subjects:
Mitotic checkpoint complex
P31comet
Spindle assembly checkpoint
Anaphase-promoting complex
CDC20
HOIP
Online Access:https://doi.org/10.1186/s13578-025-01416-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s13578-025-01416-8

Similar Items