Mathematical modeling of cyclic treatments of chronic myeloid leukemia

Cyclic treatmentstrategies in Chronic Myeloid Leukemia (CML) are characterized byalternating applications of two (or more) different drugs, given oneat a time. One of the main causes for treatment failure in CML is thegeneration of drug resistance by mutations of cancerous cells. We usemathematical...

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Bibliographic Details
Main Author: Natalia L. Komarova
Format: Article
Language:English
Published: AIMS Press 2011-03-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.289
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