Dynamic three dimensional environment for efficient and large scale generation of smooth muscle cells from hiPSCs

Abstract Background Chronic ischemic limb disease often leads to amputation, which remains a significant clinical problem. Smooth-muscle cells (SMCs) are crucially involved in the development and progression of many cardiovascular diseases, but studies with primary human SMCs have been limited by a...

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Bibliographic Details
Main Authors: Akazha Green, Yuhua Wei, Jason M. Warram, Yolanda E. Hartman, Xiaoxiao Geng, Thanh Nguyen, Lei Ye, Jianyi Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-024-04053-z
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