Beyond PrP9res) type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Beyond PrP9res) type 1/type 2 dichotomy in Creutzfeldt-Jakob disease.

Sporadic Creutzfeldt-Jakob disease (sCJD) cases are currently subclassified according to the methionine/valine polymorphism at codon 129 of the PRNP gene and the proteinase K (PK) digested abnormal prion protein (PrP(res)) identified on Western blotting (type 1 or type 2). These biochemically distin...

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Main Authors: Emmanuelle Uro-Coste, Hervé Cassard, Stéphanie Simon, Séverine Lugan, Jean-Marc Bilheude, Armand Perret-Liaudet, James W Ironside, Stéphane Haik, Christelle Basset-Leobon, Caroline Lacroux, Katell Peoch', Nathalie Streichenberger, Jan Langeveld, Mark W Head, Jacques Grassi, Jean-Jacques Hauw, Francois Schelcher, Marie Bernadette Delisle, Olivier Andréoletti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000029&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1000029&type=printable

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