Disrupted Redox Regulation and Inflammatory Response in Pyoderma Gangrenosum

Disrupted Redox Regulation and Inflammatory Response in Pyoderma Gangrenosum

Introduction. The pathophysiology of Pyoderma Gangrenosum (PG) involves altered innate and adaptive immunity, mutagenic and epigenetic changes, the autoinflammatory state, and the overexpression of cytokines. This study investigated the potential contribution of inflammation, redox signaling, and th...

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Main Authors: Simona Roxana Georgescu, Clara Matei, Corina Daniela Ene, Cristina Capusa, Mircea Tampa, Madalina Irina Mitran, Cristina Iulia Mitran, Gheorghe Nicolae, Ilinca Nicolae
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Life
Subjects:
pyoderma gangrenosum
acute phase proteins
IL-17A
Beta2 microglobulin
glutathione
Online Access:https://www.mdpi.com/2075-1729/15/4/611
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