Enhancement of systemic and lung-localized CD4<sup>+</sup> T-cell immune responses by truncation of NS1 protein of a seasonal live influenza vaccine strain
Introduction. There is a large variety of licensed influenza vaccines worldwide, but their common limitation is rather narrow specificity and inability to protect against antigenic-drift variants of influenza virus. Therefore, optimization of immunogenic and cross-protective properties of licensed i...
Saved in:
| Main Authors: | Polina I. Prokopenko, Ekaterina A. Stepanova, Victoria A. Matyushenko, Alexandra Ya. Rak, Anna K. Chistyakova, Arina D. Kostromitina, Tatyana S. Kotomina, Igor V. Kudryavtsev, Artem A. Rubinstein, Alexey S. Komlev, Larisa G. Rudenko, Irina N. Isakova-Sivak |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Central Research Institute for Epidemiology
2024-11-01
|
| Series: | Журнал микробиологии, эпидемиологии и иммунобиологии |
| Subjects: | |
| Online Access: | https://microbiol.crie.ru/jour/article/viewFile/18682/1518 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The development and maintenance of immunity against visceral leishmaniasis
by: Rahul Tiwari, et al.
Published: (2024-12-01) -
Early RSV infection aggravates asthma-related Th2 responses by increasing the number of CD4<sup>+</sup> TRM cells through upregulation of PLZF
by: Zhang Meng, et al.
Published: (2024-12-01) -
The impact of T cells on immune-related liver diseases: an overview
by: Yuzo Koda, et al.
Published: (2025-07-01) -
CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer
by: Zi-Xin Wu, et al.
Published: (2024-12-01) -
Targeting the IL-15/CD122 signaling pathway: reversing TRM cell-mediated immune memory in vitiligo
by: Xiangxi Su, et al.
Published: (2025-07-01)