New mouse models for exploring renal tumor extension into the inferior vena cava

New mouse models for exploring renal tumor extension into the inferior vena cava

Abstract Renal tumors with inferior vena cava tumor thrombus (IVCTT) remain a challenge in urology. However, in vivo models remain unavailable, which hampers the elucidation of its pathogenesis, identification of therapeutic targets, and screening for effective drugs. In this study, we initially dev...

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Main Authors: Xiubin Li, Huaikang Li, Xupeng Zhao, Jichen Wang, Di Li, Qiuyang Li, Qingjiang Xu, Shengpan Wu, Qiyang Liang, Shangwei Li, Qilong Jiao, Kan Liu, Songliang Du, Cheng Peng, Baojun Wang, Liangyou Gu, Xu Zhang, Qingbo Huang, Xin Ma
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07757-x
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https://doi.org/10.1038/s42003-025-07757-x

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