14-3-3ζ allows for adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation

14-3-3ζ allows for adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation

Objective: We previously established the scaffold protein 14-3-3ζ as a critical regulator of adipogenesis and adiposity, but whether 14-3-3ζ exerted its regulatory functions in mature adipocytes or in adipose progenitor cells (APCs) remained unclear. Methods: To decipher which cell type accounted fo...

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Bibliographic Details
Main Authors: Sabri A. Rial, Zhipeng You, Alexis Vivoli, Fédéric Paré, Daphné Sean, Amal AlKhoury, Geneviève Lavoie, Mete Civelek, Aida Martinez-Sanchez, Philippe P. Roux, Thomas M. Durcan, Gareth E. Lim
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Molecular Metabolism
Subjects:
14-3-3ζ
Adipogenesis
Energy homeostasis
Chromatin accessibility
Adipogenic genes
Epigenetic regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000663
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