Caution for Multidrug Therapy: Significant Baroreflex Afferent Neuroexcitation Coordinated by Multi-Channels/Pumps Under the Threshold Concentration of Yoda1 and Dobutamine Combination

Multi-drug therapies are common in cardiovascular disease intervention; however, io channel/pump coordination has not been tested electrophysiologically. Apparently, inward currents were not elicited by Yoda1/10 nM or Dobutamine/100 nM alone in Ah-type baroreceptor neurons, but were by their combina...

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Bibliographic Details
Main Authors: Yin-zhi Xu, Zhao-yuan Xu, Hui-xiao Fu, Mao Yue, Jia-qun Li, Chang-peng Cui, Di Wu, Bai-yan Li
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomolecules
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Online Access:https://www.mdpi.com/2218-273X/14/10/1311
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