Investigating the Mediating Role of Mental Disorders in the Relationship Between Early Sexual Intercourse and Intentional Self‐Harm: A Two‐Step and Multivariable Mendelian Randomization Study

Investigating the Mediating Role of Mental Disorders in the Relationship Between Early Sexual Intercourse and Intentional Self‐Harm: A Two‐Step and Multivariable Mendelian Randomization Study

Abstract Background Epidemiological studies have established an association between early sexual intercourse and intentional self‐harm. However, the causal mechanisms, particularly the role of mental health disorders, remain elusive. Methods In this Mendelian randomization (MR) study, we leveraged g...

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Bibliographic Details
Main Authors: Dameng Dong, Saboor Saeed, Rucheng Chen, An Chen, Weijun Zheng
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Brain and Behavior
Subjects:
early sexual intercourse
intentional self‐harm
Mendelian randomization
mental disorders
Online Access:https://doi.org/10.1002/brb3.70124
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https://doi.org/10.1002/brb3.70124

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