Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway

Phellodendrine chloride alleviates gouty arthritis through IL-6/STAT3 signaling pathway

Background: Phellodendrine, a primary bioactive constituent of Phellodendron chinense Schneid (PCS), is crucial in its pharmacological profile. Phellodendrine exhibits potent anti-nephritic properties and demonstrates a marked inhibitory effect on the cellular immune response. However, the effects o...

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Bibliographic Details
Main Authors: Yu-yao Qin, Zi-yi Qin, Tao Liang, Dong-er Qin, Sheng-yi Hua, Ming-hui Tan, Shun Guo, Fan Yang, Le Shi, Yun Yu, Guang-ji Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Immunobiology
Subjects:
Phellodendrine chloride
Gouty arthritis
Chondrocytes
STAT3
Proteoglycan
Online Access:http://www.sciencedirect.com/science/article/pii/S017129852500052X
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http://www.sciencedirect.com/science/article/pii/S017129852500052X

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