Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection.

Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection.

Alveolar macrophages (AM) are critical for defense against bacterial and fungal infections. However, a definitive role of AM in viral infections remains unclear. We here report that AM play a key role in survival to influenza and vaccinia virus infection by maintaining lung function and thereby prot...

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Main Authors: Christoph Schneider, Samuel P Nobs, Alex K Heer, Michael Kurrer, Glynis Klinke, Nico van Rooijen, Johannes Vogel, Manfred Kopf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004053&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004053&type=printable

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