A framework for complex signal processing via synthetic biological operational amplifiers

Abstract Engineering genetic circuits to process complex biological signals remains a significant challenge due to non-orthogonal signal responses that limit precise control. In this study, we introduce a framework that integrates orthogonal operational amplifiers (OAs) into standardized biological...

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Bibliographic Details
Main Authors: Wenjun Cao, Lili Liu, Qingxu Sun, Yang Shan, Ye Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62464-9
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