Amino Acid Substitutions in Bacteriocin Lactolisterin BU Reveal Functional Domains Involved in Biological Activity Against <i>Staphylococcus aureus</i>

Amino Acid Substitutions in Bacteriocin Lactolisterin BU Reveal Functional Domains Involved in Biological Activity Against <i>Staphylococcus aureus</i>

The emergence of multidrug-resistant pathogens has driven the development of novel antimicrobial peptides (AMPs) as therapeutic alternatives. Lactolisterin LBU (LBU) is a bacteriocin with promising activity against Gram-positive bacteria, including <i>Staphylococcus aureus</i>. In this s...

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Bibliographic Details
Main Authors: Lazar Gardijan, Milka Malešević, Miroslav Dinić, Aleksandar Pavić, Nikola Plačkić, Goran Jovanović, Milan Kojić
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
lactolisterin LBU
antimicrobial peptide
bacteriocin
amino acid substitution
<i>Staphylococcus aureus</i>
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Online Access:https://www.mdpi.com/1420-3049/30/15/3134
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