Safety and efficacy of direct oral anticoagulants in chronic kidney disease: a meta-analysis

Background: Direct oral anticoagulants (DOACs) have emerged as the first-line therapy for venous thromboembolism and stroke prophylaxis in atrial fibrillation. As DOACs are partially excreted renally, their safety in patients with chronic kidney disease (CKD) is unclear. Objectives: To synthesize pr...

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Main Authors: Daniel Tham, Lucy Zhao, Wenhui Yu, Jayhan Kherani, Roger Kou, Allen Li, Pei Ye Li, Ali Eshaghpour, Mark Andrew Crowther
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Research and Practice in Thrombosis and Haemostasis
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Online Access:http://www.sciencedirect.com/science/article/pii/S2475037924002796
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