A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation

The epidemiology of meconium aspiration syndrome (MAS) in term neonates is described in a population-based retrospective study of data recorded for all births from 2000 to 2007 in a French region (Burgundy). Of the 132 884 eligible term newborns, the rate of meconium-stained amniotic fluid (MSAF) wa...

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Main Authors: C. Fischer, C. Rybakowski, C. Ferdynus, P. Sagot, J. B. Gouyon
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Pediatrics
Online Access:http://dx.doi.org/10.1155/2012/321545
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author C. Fischer
C. Rybakowski
C. Ferdynus
P. Sagot
J. B. Gouyon
author_facet C. Fischer
C. Rybakowski
C. Ferdynus
P. Sagot
J. B. Gouyon
author_sort C. Fischer
collection DOAJ
description The epidemiology of meconium aspiration syndrome (MAS) in term neonates is described in a population-based retrospective study of data recorded for all births from 2000 to 2007 in a French region (Burgundy). Of the 132 884 eligible term newborns, the rate of meconium-stained amniotic fluid (MSAF) was 7.93%. The prevalence of severe MAS was 0.067% in the overall population. MAS rate was 0.11% at 37-38 weeks of gestation (WG), 0.20% at 39–41 WG, and 0.49% at 42-43 WG. Factors independently associated with severe MAS were identified by a case-control study, that is, thick meconium amniotic fluid, fetal tachycardia, Apgar score ≤3 at 1 minute, and birth in a level III facility. Our results confirm the high prevalence of MSAF after 37 WG but also show the low frequency of severe MAS in a period corresponding to the new international recommendations on the management of birth with MSAF.
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issn 1687-9740
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series International Journal of Pediatrics
spelling doaj-art-b3bec3a67e204b33a1998332427804eb2025-02-03T01:30:09ZengWileyInternational Journal of Pediatrics1687-97401687-97592012-01-01201210.1155/2012/321545321545A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of GestationC. Fischer0C. Rybakowski1C. Ferdynus2P. Sagot3J. B. Gouyon4Department of Pediatrics, CHU Dijon, 21000 Dijon, Burgundy, FranceDepartment of Pediatrics, CHU Dijon, 21000 Dijon, Burgundy, FranceDepartment of Medical Informatics and Biostatistics, CHU Dijon, 21000 Dijon, Burgundy, FranceDepartment of Medical Informatics and Biostatistics, CHU Dijon, 21000 Dijon, Burgundy, FranceDepartment of Pediatrics, CHU Dijon, 21000 Dijon, Burgundy, FranceThe epidemiology of meconium aspiration syndrome (MAS) in term neonates is described in a population-based retrospective study of data recorded for all births from 2000 to 2007 in a French region (Burgundy). Of the 132 884 eligible term newborns, the rate of meconium-stained amniotic fluid (MSAF) was 7.93%. The prevalence of severe MAS was 0.067% in the overall population. MAS rate was 0.11% at 37-38 weeks of gestation (WG), 0.20% at 39–41 WG, and 0.49% at 42-43 WG. Factors independently associated with severe MAS were identified by a case-control study, that is, thick meconium amniotic fluid, fetal tachycardia, Apgar score ≤3 at 1 minute, and birth in a level III facility. Our results confirm the high prevalence of MSAF after 37 WG but also show the low frequency of severe MAS in a period corresponding to the new international recommendations on the management of birth with MSAF.http://dx.doi.org/10.1155/2012/321545
spellingShingle C. Fischer
C. Rybakowski
C. Ferdynus
P. Sagot
J. B. Gouyon
A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation
International Journal of Pediatrics
title A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation
title_full A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation
title_fullStr A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation
title_full_unstemmed A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation
title_short A Population-Based Study of Meconium Aspiration Syndrome in Neonates Born between 37 and 43 Weeks of Gestation
title_sort population based study of meconium aspiration syndrome in neonates born between 37 and 43 weeks of gestation
url http://dx.doi.org/10.1155/2012/321545
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