Targeting TLR/IL-1R Signalling in Human Diseases

The members of Toll-like receptor/Interleukin (IL)-1 receptor (TLR/IL-1R) superfamily play a fundamental role in the immune response. These receptors detect microbial components and trigger complex signalling pathways that result in increased expression of multiple inflammatory genes. On the other h...

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Bibliographic Details
Main Authors: Maria Loiarro, Vito Ruggiero, Claudio Sette
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2010/674363
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