Targeting TLR/IL-1R Signalling in Human Diseases
The members of Toll-like receptor/Interleukin (IL)-1 receptor (TLR/IL-1R) superfamily play a fundamental role in the immune response. These receptors detect microbial components and trigger complex signalling pathways that result in increased expression of multiple inflammatory genes. On the other h...
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Main Authors: | Maria Loiarro, Vito Ruggiero, Claudio Sette |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2010/674363 |
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