Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth

Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth

Abstract Glioma growth and progression are characterized by abundant development of blood vessels that are highly aberrant and poorly functional, with detrimental consequences for drug delivery efficacy. The mechanisms driving this vessel dysmorphia during tumor progression are poorly understood. Us...

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Main Authors: Thomas Mathivet, Claire Bouleti, Matthias Van Woensel, Fabio Stanchi, Tina Verschuere, Li‐Kun Phng, Joost Dejaegher, Marly Balcer, Ken Matsumoto, Petya B Georgieva, Jochen Belmans, Raf Sciot, Christian Stockmann, Massimiliano Mazzone, Steven De Vleeschouwer, Holger Gerhardt
Format: Article
Language:English
Published: Springer Nature 2017-10-01
Series:EMBO Molecular Medicine
Subjects:
glioma
live imaging
myeloid cells
VEGF
vessel dysmorphia
Online Access:https://doi.org/10.15252/emmm.201607445
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https://doi.org/10.15252/emmm.201607445

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