A Marine-Derived Steroid from <i>Rhodococcus</i> sp., 3,12-Dioxochola-4,6-dien-24-oic Acid, Enhances Skin Re-Epithelialization and Tissue Repair

A Marine-Derived Steroid from <i>Rhodococcus</i> sp., 3,12-Dioxochola-4,6-dien-24-oic Acid, Enhances Skin Re-Epithelialization and Tissue Repair

The discovery of bioactive natural compounds from microbes holds promise for regenerative medicine. In this study, we identified and characterized a steroid-like compound, 3,12-dioxochola-4,6-dien-24-oic acid (DOCDA), from a crude extract of <i>Rhodococcus</i> sp. DOCDA significantly pro...

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Bibliographic Details
Main Authors: Mücahit Varlı, Hui Tan, Chaeyoung Lee, Jeongyun Lee, Ji Young Lee, Jeong-Hyeon Kim, Songyi Lee, Hangun Kim, Sang-Jip Nam
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Marine Drugs
Subjects:
wound healing
tissue repair
<i>Rhodococcus</i> sp.
marine drugs
3,12-dioxochola-4,6-dien-24-oic acid
glucocorticoid receptor
Online Access:https://www.mdpi.com/1660-3397/23/7/292
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