Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Improve 5-FU-Induced Delayed Wound Healing by Mitochondrial Transfer

Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Improve 5-FU-Induced Delayed Wound Healing by Mitochondrial Transfer

<b>Background/Objectives:</b> This study aimed to explore the therapeutic potential of umbilical mesenchymal stem cell-derived apoptotic vesicles (UMSC-apoVs) in a 5-Fluorouracil (5-FU)-induced impairment in skin wound healing. <b>Methods:</b> UMSC-apoVs were isolated from UM...

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Bibliographic Details
Main Authors: Hongbin Lai, Ling Lin, Yanrui Pan, Boqun Wang, Lan Ma, Wei Zhao
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
delayed wound healing
5-fluorouracil
umbilical cord mesenchymal stem cell-derived apoptotic vesicles
mitochondrial transfer
skin mesenchymal stem cells
Online Access:https://www.mdpi.com/1999-4923/17/4/453
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