Pharmacological inhibition of SUMOylation with TAK-981 mimics genetic HypoSUMOylation in murine perigonadal white adipose tissue
Post-translational modification by the small ubiquitin-like modifier (SUMO) is essential for cellular differentiation and homeostasis. Here, we investigate the role of SUMOylation in adipose tissue development using TAK-981, a pharmacological inhibitor of SUMOylation. Administration of TAK-981 to mi...
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| Main Authors: | Damien Dufour, Xu Zhao, Florian Chaleil, Patrizia Maria Christiane Nothnagel, Magnar Bjørås, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Chymkowitch |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Adipocyte |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/21623945.2025.2474107 |
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