The insula represents a key neurobiological pain hub in psoriatic arthritis

The insula represents a key neurobiological pain hub in psoriatic arthritis

Abstract Background Pain remains a principal complaint for people with psoriatic arthritis (PsA), despite successful mitigation of inflammation. This situation alludes to the co-existence of distinct pain mechanisms. Nociceptive and nociplastic mechanisms are clinically challenging to distinguish. A...

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Main Authors: Flavia Sunzini, Kristian Stefanov, Salim Al-Wasity, Chelsea Kaplan, Andrew Schrepf, Noah Waller, Steven Harte, Richard Harris, Daniel J. Clauw, John McLean, Stefan Siebert, Carl S. Goodyear, Gordon D. Waiter, Neil Basu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Arthritis Research & Therapy
Subjects:
Chronic pain
Psoriatic arthritis
Neuroimaging
Fibromyalgia
Insula
Online Access:https://doi.org/10.1186/s13075-025-03526-7
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https://doi.org/10.1186/s13075-025-03526-7

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