Synthesis and biological evaluation of norfloxacin – 1,2,3-triazole hybrids as antitumor, antibacterial, and antioxidant agents

Synthesis and biological evaluation of norfloxacin – 1,2,3-triazole hybrids as antitumor, antibacterial, and antioxidant agents

Six norfloxacin-1,2,3-triazole hybrids(7a-e) were synthesized via click reaction. Norfloxacin-1,2,3-triazole hybrids were screened for anti-cancer activity against different cancer cell lines DLD1, MCF-7, A549 and HDF. Two hybrids, 7a and 7d, demonstrated a significant potent anti-cancer effect agai...

Full description

Saved in:
Bibliographic Details
Main Authors: Samir Al-Taweel, Yousef Al-Saraireh, Salah Al-Trawneh, Solhe Alshahateet, Rakan Al- Tarawneh, Wael Zereini, Omar Al-Qaralleh, Ahmed Al-sarayreh, Mohammad Salem Hareedy, Y.M. Abuhalaweh, Amer Hussien Tarawneh
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Results in Chemistry
Subjects:
Click reaction
Norfloxacin-1,2,3-triazole hybrids
Anti-tumor
Cell lines DLD1
MCF-7 and A549
Normal HDF cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625004886
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2211715625004886

Similar Items