Systematic mediation and interaction analyses of kidney function genetic loci in a general population study.

Chronic kidney disease (CKD) is a complex disease affecting >10% of the global population, with large between- and within-continent variability reflecting major environmental determinants. To identify molecular targets for treatment and prevention, genome-wide association study meta-analyses (GWA...

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Main Authors: Dariush Ghasemi-Semeskandeh, David Emmert, Eva König, Luisa Foco, Martin Gögele, Mohamed S Sarhan, Laura Barin, Ryosuke Fujii, Christian Fuchsberger, Dorien J M Peters, Peter P Pramstaller, Cristian Pattaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323057
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