MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity

MIRO2 promotes cancer invasion and metastasis via MYO9B suppression of RhoA activity

Summary: Metastasis to vital organs remains the leading cause of cancer-related deaths, emphasizing an urgent need for actionable targets in advanced-stage cancer. The role of mitochondrial Rho GTPase 2 (MIRO2) in prostate cancer growth was recently reported; however, whether MIRO2 is important for...

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Bibliographic Details
Main Authors: Dillon P. Boulton, Connor J. Hughes, Valentina Vaira, Alessandro Del Gobbo, Alessandro Palleschi, Marco Locatelli, Etienne Danis, Masoom Raza, Andrew J. Neumann, Stephen Connor Purdy, Raymundo Lerma, John Meshki, Heide L. Ford, Rytis Prekeris, Colm Morrissey, M. Cecilia Caino
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
CP: Cancer
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014712
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http://www.sciencedirect.com/science/article/pii/S2211124724014712

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