Chloroquine inhibits artificial oocyte activation induced by ethanol or Sr2+ but not by sperm in mice
Calcium release from the endoplasmic reticulum via sperm-derived phospholipase C zeta is crucial for oocyte activation during fertilization. Chloroquine (CQ) inhibits the increase in cytoplasmic calcium. This study investigated the effects of CQ on fertilization and oocyte activation. Oocytes were c...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Society for Reproduction and Development
2024-12-01
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| Series: | The Journal of Reproduction and Development |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jrd/71/1/71_2024-089/_pdf/-char/en |
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