Entrectinib-induced Brugada syndrome leading to ventricular tachycardia in a patient with ROS1 fusion-positive lung adenocarcinoma

Entrectinib-induced Brugada syndrome leading to ventricular tachycardia in a patient with ROS1 fusion-positive lung adenocarcinoma

A 65-year-old male presented to the emergency room after experiencing syncope while driving, causing a self-inflicted accident. He had previously been diagnosed with stage IV A (cTXN2M1a) lung adenocarcinoma with C-ROS oncogene 1 (ROS1) fusion gene, wherein entrectinib (a multikinase inhibitor of RO...

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Bibliographic Details
Main Authors: Nobuo Ishiguro, Takeshi Mori, Makito Kaneshiro, Shin Hasegawa, Akimitsu Tanaka, Miyuki Ando, Kazuo Kato
Format: Article
Language:English
Published: SMC MEDIA SRL 2025-04-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
entrectinib
drug-induced brugada syndrome
ventricular tachycardia
ros1 fusion-positive non-small-cell lung cancer
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/5232
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