PI3K/AKT signaling mediates stress-inducible amyloid formation through c-Myc

Summary: In response to environmental stress, eukaryotic cells reversibly form functional amyloid aggregates called amyloid bodies (A-bodies). While these solid-like biomolecular condensates share many biophysical characteristics with pathological amyloids, A-bodies are non-toxic, and they induce a...

Full description

Saved in:
Bibliographic Details
Main Authors: Emma Lacroix, Evgenia A. Momchilova, Sahil Chandhok, Mythili Padavu, Richard Zapf, Timothy E. Audas
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725003882
Tags: Add Tag
No Tags, Be the first to tag this record!