Resolvin D1 improves bleomycin-induced alveolar maturation arrest in newborn rats

Resolvin D1 improves bleomycin-induced alveolar maturation arrest in newborn rats

Abstract Sustained, non-resolving inflammation is a fundamental mechanism that causes bronchopulmonary dysplasia (BPD). Specialized pro-resolving mediators (SPMs) are attracting attention as the new endogenous anti-inflammatory agents because they facilitate only the resolution phase of inflammation...

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Bibliographic Details
Main Authors: Jun Shinohara, Tohru Ogihara, Shigeo Yamaoka, Yutaro Kawamura, Daisuke Nishioka, Kazumi Honda, Yumiko Yoshimura, Akira Ashida
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Bronchopulmonary dysplasia
Resolvin D1
Insulin-like growth factor-1
Tenascin-C
Specialized pro-resolving mediators
Online Access:https://doi.org/10.1038/s41598-025-12739-4
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https://doi.org/10.1038/s41598-025-12739-4

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