HJURP modulates cell proliferation and chemoresistance via the MYC/TOP2A transcriptional axis in gastric cancer

BackgroundThe histone chaperone Holliday Junction Recognition Protein (HJURP) has been associated with multiple types of cancers, but its role in GC is not yet fully understood. Considering its functions in centromere stability and DNA repair, investigating HJURP’s role in GC may offer novel therape...

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Bibliographic Details
Main Authors: Xu Li, Xiwen Li, Yanlin Ren, Ling Wang, Zehao Mao, Shikun Gao, Peng Ma, Junjie Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1566293/full
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